ADSCC, Yas Clinic pioneer CAR-T cell therapy for life-threatening lupus, antiphospholipid syndrome
Abu Dhabi Stem Cells Centre (ADSCC), in collaboration with Yas Clinic Khalifa City, has achieved a groundbreaking success by administering CAR-T cell therapy to a 38-year-old male patient battling severe systemic lupus erythematosus (SLE) and triple-positive antiphospholipid syndrome (APS). This remarkable feat signifies a major leap forward in treating complex autoimmune conditions right here in Abu Dhabi and the UAE.
A Challenging Case
The patient’s medical history presented a significant challenge, marked by diffuse alveolar hemorrhage, recurrent subdural hematomas, deep vein thrombosis, pulmonary embolism, IVC thrombosis, and Budd-Chiari syndrome. Despite intensive treatment using immunosuppressants and anticoagulants, the condition remained active and posed a serious threat to his life.
A Bold Step Forward
ADSCC’s success with CAR-T therapy underscores its unwavering dedication to research, innovation, and prioritizing patient well-being.
“The successful delivery of CAR-T therapy in this case reflects a bold step forward in treating severe autoimmune conditions,” said Prof. Yendry Ventura, Chief Executive Officer of ADSCC. “It is the result of years of commitment to research, innovation, and patient-centred care.”
Promising Results and Ongoing Care
Following the treatment, the patient has shown encouraging signs of clinical improvement and immune system reset and has been safely discharged from the hospital. A comprehensive multidisciplinary care plan is in place, involving long-term follow-up and thorough laboratory assessments, to ensure sustained disease remission and effective management of clotting risks.
Transforming Regional Healthcare
Dr. Maysoon Al Karam, Chief Medical Officer at Yas Clinic Khalifa City, emphasized the importance of this achievement:
“This groundbreaking continuous achievement in applying CAR-T cell therapy to treat severe autoimmune conditions like lupus and antiphospholipid syndrome marks a transformative milestone in regional healthcare.”
This collaborative effort highlights ADSCC’s commitment to pushing the boundaries of medical science and providing cutting-edge treatments to patients in Abu Dhabi and beyond, reinforcing its position as a leader in innovative healthcare solutions.




